CRYAB anticorps (C-Term)

N° du produit ABIN2783274

L’anticorps Lapin Polyclonal anti-CRYAB a été validé pour WB. Il convient pour détecter CRYAB dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Mouton, Chien, Cobaye, Lapin et Cheval.

Aperçu rapide pour CRYAB anticorps (C-Term) (ABIN2783274)

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Mouton, Chien, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYAB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRYAB anticorps

Épitope: C-Term

Séquence: KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against CRYAB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CRYAB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 175 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRYAB

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Autre désignation: CRYAB

Sujet: Alpha crystallins are composed of: alpha-A and alpha-B, for acidic and basic, respectively. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy.
Alias Symbols: CRYA2, CTPP2, HSPB5
Protein Interaction Partner: CRYAB, CRYAA, KRTAP19-5, KRTAP8-1, TRAPPC6A, MRPL11, TNPO2, ACOT7, HSPB1, CASP7, CASP3, CASP2, PIDD1, DDX20, CRADD, B2M, APOC2, XIAP, CASP12, SOD1, HSPB2, HBA1, CASP9, CASP8, CASP6, ASB5, SMAD4, TRIM33, UBC, CCL22, CTNNB1, CRYGD, CDH1, SNCA, GFAP, FGF2, F
Protein Size: 175

Poids moléculaire: 20 kDa

ID gène: 1410

NCBI Accession: NM_001885

UniProt: P02511